PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

DEERFIELD MANAGEMENT COMPANY, L.P.'s Holding History (CIK: 0001009258)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021

Shares 3,769,795 Value ($000) $34,607 Avg Close $10.13 Range $8.74 - $11.95

Q1 2021

Shares 3,769,795 Value ($000) $36,642 Avg Close $11.17 Range $9.19 - $14.14

Q4 2020

Shares 3,959,741 Value ($000) $40,627 Avg Close $10.13 Range $7.48 - $13.16

Q3 2020

Shares 2,826,327 Value ($000) $28,518 Avg Close $10.18 Range $9.04 - $12.90

Q1 2020

Shares 963,212 Value ($000) $8,130 Avg Close $9.72 Range $5.50 - $15.00

Q4 2019

Shares 396,472 Value ($000) $3,469 Avg Close $8.28 Range $6.26 - $11.10

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2021	3,769,795	$34,607	$10.13	$8.74 - $11.95
Q1 2021	3,769,795	$36,642	$11.17	$9.19 - $14.14
Q4 2020	3,959,741	$40,627	$10.13	$7.48 - $13.16
Q3 2020	2,826,327	$28,518	$10.18	$9.04 - $12.90
Q1 2020	963,212	$8,130	$9.72	$5.50 - $15.00
Q4 2019	396,472	$3,469	$8.28	$6.26 - $11.10