PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017

Shares 50,000 Value ($000) $4,943 Avg Close $111.90 Range $92.36 - $136.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2017	50,000	$4,943	$111.90	$92.36 - $136.90