PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

CAPITAL INTERNATIONAL SARL's Holding History (CIK: 0001065349)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 108,005 Value ($000) $8,468 Avg Close $78.49 Range $56.11 - $94.93

Q3 2015

Shares 109,405 Value ($000) $8,245 Avg Close $94.57 Range $70.39 - $119.36

Q2 2015

Shares 64,405 Value ($000) $7,519 Avg Close $181.09 Range $112.32 - $244.90

Q1 2015

Shares 58,640 Value ($000) $13,845 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 53,700 Value ($000) $10,164 Avg Close $221.87 Range $181.60 - $255.43

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	108,005	$8,468	$78.49	$56.11 - $94.93
Q3 2015	109,405	$8,245	$94.57	$70.39 - $119.36
Q2 2015	64,405	$7,519	$181.09	$112.32 - $244.90
Q1 2015	58,640	$13,845	$213.77	$183.50 - $252.92
Q4 2014	53,700	$10,164	$221.87	$181.60 - $255.43