PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

CAPITAL INTERNATIONAL LTD /CA/'s Holding History (CIK: 0001065350)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 139,897 Value ($000) $10,968 Avg Close $78.49 Range $56.11 - $94.93

Q3 2015

Shares 145,697 Value ($000) $10,980 Avg Close $94.57 Range $70.39 - $119.36

Q2 2015

Shares 90,935 Value ($000) $10,617 Avg Close $181.09 Range $112.32 - $244.90

Q1 2015

Shares 62,735 Value ($000) $14,812 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 55,400 Value ($000) $10,486 Avg Close $221.87 Range $181.60 - $255.43

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	139,897	$10,968	$78.49	$56.11 - $94.93
Q3 2015	145,697	$10,980	$94.57	$70.39 - $119.36
Q2 2015	90,935	$10,617	$181.09	$112.32 - $244.90
Q1 2015	62,735	$14,812	$213.77	$183.50 - $252.92
Q4 2014	55,400	$10,486	$221.87	$181.60 - $255.43