PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

PERCEPTIVE ADVISORS LLC's Holding History (CIK: 0001224962)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 564,579 Value ($000) $27,667 Avg Close $57.95 Range $47.00 - $68.90

Q1 2018

Shares 442,179 Value ($000) $30,090 Avg Close $74.88 Range $56.15 - $101.50

Q4 2017

Shares 703,820 Value ($000) $69,573 Avg Close $111.90 Range $92.36 - $136.90

Q3 2017

Shares 923,820 Value ($000) $110,627 Avg Close $93.01 Range $71.14 - $120.85

Q2 2017

Shares 733,320 Value ($000) $64,092 Avg Close $55.94 Range $28.35 - $92.00

Q4 2016

Shares 7,344 Value ($000) $225 Avg Close $43.24 Range $29.85 - $68.05

Q3 2016

Shares 7,344 Value ($000) $492 Avg Close $50.56 Range $28.14 - $73.27

Q3 2014

Shares 11,000 Value ($000) $2,624 Avg Close $205.34 Range $57.25 - $279.37

Q1 2014

Shares 735 Value ($000) $76 Avg Close $117.54 Range $97.31 - $143.65

Q4 2013

Shares 735 Value ($000) $76 Avg Close $58.69 Range $33.70 - $112.46

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	564,579	$27,667	$57.95	$47.00 - $68.90
Q1 2018	442,179	$30,090	$74.88	$56.15 - $101.50
Q4 2017	703,820	$69,573	$111.90	$92.36 - $136.90
Q3 2017	923,820	$110,627	$93.01	$71.14 - $120.85
Q2 2017	733,320	$64,092	$55.94	$28.35 - $92.00
Q4 2016	7,344	$225	$43.24	$29.85 - $68.05
Q3 2016	7,344	$492	$50.56	$28.14 - $73.27
Q3 2014	11,000	$2,624	$205.34	$57.25 - $279.37
Q1 2014	735	$76	$117.54	$97.31 - $143.65
Q4 2013	735	$76	$58.69	$33.70 - $112.46