PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2013

Shares 25,000 Value ($000) $2,588 Avg Close $58.69 Range $33.70 - $112.46

Q3 2013

Shares 100,000 Value ($000) $5,366 Avg Close $53.90 Range $44.39 - $62.66

Q2 2013

Shares 83,333 Value ($000) $3,697 Avg Close $35.25 Range $27.40 - $45.69

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2013	25,000	$2,588	$58.69	$33.70 - $112.46
Q3 2013	100,000	$5,366	$53.90	$44.39 - $62.66
Q2 2013	83,333	$3,697	$35.25	$27.40 - $45.69