PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

CAPITAL FUND MANAGEMENT S.A.'s Holding History (CIK: 0001323645)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021

Shares 36,706 Value ($000) $257,309 Avg Close $7.49 Range $6.48 - $9.48

Q2 2021

Shares 35,059 Value ($000) $321,841 Avg Close $10.13 Range $8.74 - $11.95

Q1 2021

Shares 33,425 Value ($000) $324,891 Avg Close $11.17 Range $9.19 - $14.14

Q4 2020

Shares 32,316 Value ($000) $331,562 Avg Close $10.13 Range $7.48 - $13.16

Q3 2020

Shares 23,297 Value ($000) $235,066 Avg Close $10.18 Range $9.04 - $12.90

Q2 2019

Shares 94,439 Value ($000) $1,200 Avg Close $23.03 Range $12.22 - $36.75

Q2 2018

Shares 10,003 Value ($000) $592 Avg Close $57.95 Range $47.00 - $68.90

Q1 2018

Shares 24,794 Value ($000) $1,687 Avg Close $74.88 Range $56.15 - $101.50

Q1 2017

Shares 87,755 Value ($000) $3,264 Avg Close $36.49 Range $28.95 - $45.44

Q3 2016

Shares 8,590 Value ($000) $576 Avg Close $50.56 Range $28.14 - $73.27

Q4 2014

Shares 2,999 Value ($000) $568 Avg Close $221.87 Range $181.60 - $255.43

Q2 2014

Shares 25,936 Value ($000) $1,712 Avg Close $71.11 Range $53.63 - $118.22

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2021	36,706	$257,309	$7.49	$6.48 - $9.48
Q2 2021	35,059	$321,841	$10.13	$8.74 - $11.95
Q1 2021	33,425	$324,891	$11.17	$9.19 - $14.14
Q4 2020	32,316	$331,562	$10.13	$7.48 - $13.16
Q3 2020	23,297	$235,066	$10.18	$9.04 - $12.90
Q2 2019	94,439	$1,200	$23.03	$12.22 - $36.75
Q2 2018	10,003	$592	$57.95	$47.00 - $68.90
Q1 2018	24,794	$1,687	$74.88	$56.15 - $101.50
Q1 2017	87,755	$3,264	$36.49	$28.95 - $45.44
Q3 2016	8,590	$576	$50.56	$28.14 - $73.27
Q4 2014	2,999	$568	$221.87	$181.60 - $255.43
Q2 2014	25,936	$1,712	$71.11	$53.63 - $118.22