PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015

Shares 3,100 Value ($000) $362 Avg Close $181.09 Range $112.32 - $244.90

Q1 2015

Shares 3,100 Value ($000) $732 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 3,100 Value ($000) $587 Avg Close $221.87 Range $181.60 - $255.43

Q3 2014

Shares 3,100 Value ($000) $740 Avg Close $205.34 Range $57.25 - $279.37

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2015	3,100	$362	$181.09	$112.32 - $244.90
Q1 2015	3,100	$732	$213.77	$183.50 - $252.92
Q4 2014	3,100	$587	$221.87	$181.60 - $255.43
Q3 2014	3,100	$740	$205.34	$57.25 - $279.37