PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

Grantham, Mayo, Van Otterloo & Co. LLC's Holding History (CIK: 0001352662)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016

Shares 2,010,801 Value ($000) $59,057 Avg Close $45.19 Range $25.20 - $77.99

Q4 2015

Shares 2,899,776 Value ($000) $227,342 Avg Close $78.49 Range $56.11 - $94.93

Q3 2015

Shares 1,676,678 Value ($000) $126,354 Avg Close $94.57 Range $70.39 - $119.36

Q2 2015

Shares 1,426,738 Value ($000) $166,572 Avg Close $181.09 Range $112.32 - $244.90

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2016	2,010,801	$59,057	$45.19	$25.20 - $77.99
Q4 2015	2,899,776	$227,342	$78.49	$56.11 - $94.93
Q3 2015	1,676,678	$126,354	$94.57	$70.39 - $119.36
Q2 2015	1,426,738	$166,572	$181.09	$112.32 - $244.90