PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017

Shares 20,000 Value ($000) $1,977 Avg Close $111.90 Range $92.36 - $136.90

Q3 2017

Shares 20,000 Value ($000) $2,395 Avg Close $93.01 Range $71.14 - $120.85

Q1 2014

Shares 44,900 Value ($000) $4,676 Avg Close $117.54 Range $97.31 - $143.65

Q4 2013

Shares 42,100 Value ($000) $4,359 Avg Close $58.69 Range $33.70 - $112.46

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2017	20,000	$1,977	$111.90	$92.36 - $136.90
Q3 2017	20,000	$2,395	$93.01	$71.14 - $120.85
Q1 2014	44,900	$4,676	$117.54	$97.31 - $143.65
Q4 2013	42,100	$4,359	$58.69	$33.70 - $112.46