PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q3 2024

Shares 12,173 Value ($000) $31 Avg Close $3.03 Range $2.23 - $4.13

Q2 2022

Shares 14,156 Value ($000) $40 Avg Close $2.49 Range $1.60 - $3.42

Q3 2019

Shares 10,396 Value ($000) $112 Avg Close $10.80 Range $8.45 - $13.35

Q1 2019

Shares 5,263 Value ($000) $204 Avg Close $30.54 Range $19.86 - $43.90

Q2 2017

Shares 3,207 Value ($000) $280 Avg Close $55.94 Range $28.35 - $92.00

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2024	12,173	$31	$3.03	$2.23 - $4.13
Q2 2022	14,156	$40	$2.49	$1.60 - $3.42
Q3 2019	10,396	$112	$10.80	$8.45 - $13.35
Q1 2019	5,263	$204	$30.54	$19.86 - $43.90
Q2 2017	3,207	$280	$55.94	$28.35 - $92.00