PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

Connor, Clark & Lunn Investment Management Ltd.'s Holding History (CIK: 0001596800)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 875,301 Value ($000) $5,208 Avg Close $5.31 Range $4.58 - $6.27

Q3 2025

Shares 943,472 Value ($000) $5,010 Avg Close $4.24 Range $3.03 - $6.07

Q2 2025

Shares 900,256 Value ($000) $3,088 Avg Close $3.19 Range $2.58 - $3.82

Q1 2025

Shares 831,689 Value ($000) $2,462 Avg Close $3.13 Range $2.69 - $4.06

Q4 2024

Shares 487,368 Value ($000) $1,486 Avg Close $2.91 Range $2.32 - $3.51

Q3 2024

Shares 368,455 Value ($000) $940 Avg Close $3.03 Range $2.23 - $4.13

Q2 2024

Shares 354,514 Value ($000) $1,156 Avg Close $4.39 Range $2.81 - $6.06

Q1 2024

Shares 385,863 Value ($000) $2,045 Avg Close $5.38 Range $4.12 - $7.73

Q4 2023

Shares 196,659 Value ($000) $852 Avg Close $3.31 Range $2.13 - $4.59

Q3 2023

Shares 199,767 Value ($000) $525 Avg Close $3.41 Range $2.57 - $4.19

Q2 2023

Shares 199,767 Value ($000) $705 Avg Close $3.12 Range $2.53 - $3.75

Q1 2023

Shares 183,945 Value ($000) $568 Avg Close $3.77 Range $2.13 - $4.89

Q4 2022

Shares 183,270 Value ($000) $775 Avg Close $3.45 Range $2.08 - $5.16

Q3 2022

Shares 149,294 Value ($000) $354 Avg Close $2.92 Range $2.23 - $4.07

Q2 2022

Shares 77,591 Value ($000) $221 Avg Close $2.49 Range $1.60 - $3.42

Q1 2022

Shares 90,731 Value ($000) $261 Avg Close $2.59 Range $2.06 - $3.38

Q4 2021

Shares 100,215 Value ($000) $305 Avg Close $4.34 Range $2.78 - $7.11

Q1 2020

Shares 11,467 Value ($000) $97 Avg Close $9.72 Range $5.50 - $15.00

Q3 2016

Shares 3,925 Value ($000) $263 Avg Close $50.56 Range $28.14 - $73.27

Q2 2016

Shares 26,725 Value ($000) $796 Avg Close $31.26 Range $19.74 - $39.67

Q1 2016

Shares 27,250 Value ($000) $800 Avg Close $45.19 Range $25.20 - $77.99

Q4 2015

Shares 29,350 Value ($000) $2,301 Avg Close $78.49 Range $56.11 - $94.93

Q3 2015

Shares 35,875 Value ($000) $2,704 Avg Close $94.57 Range $70.39 - $119.36

Q2 2015

Shares 35,600 Value ($000) $4,156 Avg Close $181.09 Range $112.32 - $244.90

Q1 2015

Shares 35,000 Value ($000) $8,264 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 20,900 Value ($000) $3,956 Avg Close $221.87 Range $181.60 - $255.43

Q3 2014

Shares 8,600 Value ($000) $2,052 Avg Close $205.34 Range $57.25 - $279.37

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	875,301	$5,208	$5.31	$4.58 - $6.27
Q3 2025	943,472	$5,010	$4.24	$3.03 - $6.07
Q2 2025	900,256	$3,088	$3.19	$2.58 - $3.82
Q1 2025	831,689	$2,462	$3.13	$2.69 - $4.06
Q4 2024	487,368	$1,486	$2.91	$2.32 - $3.51
Q3 2024	368,455	$940	$3.03	$2.23 - $4.13
Q2 2024	354,514	$1,156	$4.39	$2.81 - $6.06
Q1 2024	385,863	$2,045	$5.38	$4.12 - $7.73
Q4 2023	196,659	$852	$3.31	$2.13 - $4.59
Q3 2023	199,767	$525	$3.41	$2.57 - $4.19
Q2 2023	199,767	$705	$3.12	$2.53 - $3.75
Q1 2023	183,945	$568	$3.77	$2.13 - $4.89
Q4 2022	183,270	$775	$3.45	$2.08 - $5.16
Q3 2022	149,294	$354	$2.92	$2.23 - $4.07
Q2 2022	77,591	$221	$2.49	$1.60 - $3.42
Q1 2022	90,731	$261	$2.59	$2.06 - $3.38
Q4 2021	100,215	$305	$4.34	$2.78 - $7.11
Q1 2020	11,467	$97	$9.72	$5.50 - $15.00
Q3 2016	3,925	$263	$50.56	$28.14 - $73.27
Q2 2016	26,725	$796	$31.26	$19.74 - $39.67
Q1 2016	27,250	$800	$45.19	$25.20 - $77.99
Q4 2015	29,350	$2,301	$78.49	$56.11 - $94.93
Q3 2015	35,875	$2,704	$94.57	$70.39 - $119.36
Q2 2015	35,600	$4,156	$181.09	$112.32 - $244.90
Q1 2015	35,000	$8,264	$213.77	$183.50 - $252.92
Q4 2014	20,900	$3,956	$221.87	$181.60 - $255.43
Q3 2014	8,600	$2,052	$205.34	$57.25 - $279.37