PYXIS ONCOLOGY INC

Institution	Shares	Value ($000)
HealthInvest Partners AB	617,245	$710
ExodusPoint Capital Management, LP	317,769	$365
Graham Capital Management, L.P.	183,942	$212
Maia Wealth LLC	21,959	$30
MARSHALL WACE, LLP	389,764	$448
PACES FERRY WEALTH ADVISORS, LLC	11,440	$13
FOX RUN MANAGEMENT, L.L.C.	22,566	$26
Quadrature Capital Ltd	100,536	$116
Point72 Asset Management, L.P.	188,136	$216
OMERS ADMINISTRATION Corp	67,000	$77
TORONTO DOMINION BANK	75,000	$86
Lighthouse Investment Partners, LLC	28,860	$33
Avanza Fonder AB	27,345	$31
AMERICAN CENTURY COMPANIES INC	31,936	$37
Engineers Gate Manager LP	22,816	$26
Jefferies Financial Group Inc.	16,000	$18
BALYASNY ASSET MANAGEMENT L.P.	8,227	$9
FEDERATED HERMES, INC.	1,894	$2
US BANCORP \DE\	94	$0

Increased Positions (24)

Laurion Capital Management LP

Value ($000) $5,516 (-31.5%) Shares 4,796,479 (+32.3%)

683 Capital Management, LLC

Value ($000) $1,026 (-12.0%) Shares 891,910 (+69.9%)

XTX Topco Ltd

Value ($000) $332 (+745.9%) Shares 289,033 (+1533.0%)

JANE STREET GROUP, LLC

Value ($000) $904 (+34.1%) Shares 786,010 (+158.8%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $838 (-34.5%) Shares 728,380 (+26.4%)

VANGUARD GROUP INC

Value ($000) $2,686 (-44.1%) Shares 2,335,768 (+7.9%)

Qube Research & Technologies Ltd

Value ($000) $168 (+145.2%) Shares 145,813 (+373.3%)

BlackRock, Inc.

Value ($000) $902 (-40.6%) Shares 784,077 (+14.7%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $121 (+17.6%) Shares 105,528 (+126.9%)

STATE STREET CORP

Value ($000) $278 (-38.1%) Shares 241,637 (+19.6%)

GEODE CAPITAL MANAGEMENT, LLC

Value ($000) $664 (-45.1%) Shares 577,211 (+6.0%)

BNP PARIBAS ARBITRAGE, SA

Value ($000) $28 (+632.5%) Shares 24,279 (+1314.0%)

LPL Financial LLC

Value ($000) $40 (+29.9%) Shares 35,102 (+150.7%)

UBS Group AG

Value ($000) $452 (-45.6%) Shares 392,766 (+5.1%)

DIMENSIONAL FUND ADVISORS LP

Value ($000) $58 (-29.0%) Shares 50,066 (+37.1%)

NewEdge Advisors, LLC

Value ($000) $12 (+2024.0%) Shares 10,250 (+4000.0%)

WELLS FARGO & COMPANY/MN

Value ($000) $3 (+315.2%) Shares 2,285 (+701.8%)

CITIGROUP INC

Value ($000) $3 (+17.4%) Shares 2,902 (+126.5%)

OSAIC HOLDINGS, INC.

Value ($000) $20 (+1.7%) Shares 17,224 (+13.2%)

NORTHERN TRUST CORP

Value ($000) $117 (-47.6%) Shares 101,948 (+1.2%)

Institution	Prev Shares	Curr Shares	Change
Laurion Capital Management LP	3,625,974	4,796,479	+1,170,505 (+32.3%)
683 Capital Management, LLC	525,000	891,910	+366,910 (+69.9%)
XTX Topco Ltd	17,699	289,033	+271,334 (+1533.0%)
JANE STREET GROUP, LLC	303,700	786,010	+482,310 (+158.8%)
RENAISSANCE TECHNOLOGIES LLC	576,336	728,380	+152,044 (+26.4%)
VANGUARD GROUP INC	2,163,962	2,335,768	+171,806 (+7.9%)
Qube Research & Technologies Ltd	30,808	145,813	+115,005 (+373.3%)
BlackRock, Inc.	683,702	784,077	+100,375 (+14.7%)
TWO SIGMA INVESTMENTS, LP	46,501	105,528	+59,027 (+126.9%)
STATE STREET CORP	202,055	241,637	+39,582 (+19.6%)
GEODE CAPITAL MANAGEMENT, LLC	544,508	577,211	+32,703 (+6.0%)
BNP PARIBAS ARBITRAGE, SA	1,717	24,279	+22,562 (+1314.0%)
LPL Financial LLC	14,002	35,102	+21,100 (+150.7%)
UBS Group AG	373,727	392,766	+19,039 (+5.1%)
DIMENSIONAL FUND ADVISORS LP	36,516	50,066	+13,550 (+37.1%)
NewEdge Advisors, LLC	250	10,250	+10,000 (+4000.0%)
WELLS FARGO & COMPANY/MN	285	2,285	+2,000 (+701.8%)
CITIGROUP INC	1,281	2,902	+1,621 (+126.5%)
OSAIC HOLDINGS, INC.	15,221	17,224	+2,003 (+13.2%)
NORTHERN TRUST CORP	100,773	101,948	+1,175 (+1.2%)

Decreased Positions (19)

Velan Capital Investment Management LP

Value ($000) $46 (-62.3%) Shares 40,000 (-27.3%)

CITADEL ADVISORS LLC

Value ($000) $280 (-62.6%) Shares 243,589 (-27.8%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $855 (-52.8%) Shares 743,107 (-8.9%)

GOLDMAN SACHS GROUP INC

Value ($000) $99 (-64.4%) Shares 86,145 (-31.3%)

TWO SIGMA ADVISERS, LP

Value ($000) $26 (-77.7%) Shares 22,624 (-56.9%)

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $125 (-59.2%) Shares 108,414 (-21.2%)

BANK OF AMERICA CORP /DE/

Value ($000) $676 (-50.6%) Shares 587,851 (-4.6%)

ROYAL BANK OF CANADA

Value ($000) $64 (-63.0%) Shares 55,551 (-28.8%)

MORGAN STANLEY

Value ($000) $103 (-56.6%) Shares 89,222 (-16.3%)

COMMONWEALTH EQUITY SERVICES, LLC

Value ($000) $46 (+33517.7%) Shares 39,755 (-35.0%)

BARCLAYS PLC

Value ($000) $69 (-70.5%) Shares 60,385 (-5.8%)

BRIDGEWAY CAPITAL MANAGEMENT, LLC

Value ($000) $84 (-50.9%) Shares 72,700 (-5.2%)

FMR LLC

Value ($000) $15 (-56.9%) Shares 12,858 (-16.8%)

Tower Research Capital LLC (TRC)

Value ($000) $12 (-56.9%) Shares 10,810 (-16.7%)

China Universal Asset Management Co., Ltd.

Value ($000) $12 (-51.7%) Shares 10,146 (-6.7%)

Cetera Investment Advisers

Value ($000) $31 (-49.1%) Shares 27,260 (-1.8%)

GF FUND MANAGEMENT CO. LTD.

Value ($000) $1 (-50.4%) Shares 1,277 (-4.3%)

SBI Securities Co., Ltd.

Value ($000) $0 (-75.0%) Shares 1 (-50.0%)

CWM, LLC

Value ($000) $0 (-100.0%) Shares 70 (-83.1%)

Institution	Prev Shares	Curr Shares	Change
Velan Capital Investment Management LP	55,000	40,000	-15,000 (-27.3%)
CITADEL ADVISORS LLC	337,359	243,589	-93,770 (-27.8%)
MILLENNIUM MANAGEMENT LLC	815,331	743,107	-72,224 (-8.9%)
GOLDMAN SACHS GROUP INC	125,454	86,145	-39,309 (-31.3%)
TWO SIGMA ADVISERS, LP	52,524	22,624	-29,900 (-56.9%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP	137,531	108,414	-29,117 (-21.2%)
BANK OF AMERICA CORP /DE/	615,922	587,851	-28,071 (-4.6%)
ROYAL BANK OF CANADA	77,980	55,551	-22,429 (-28.8%)
MORGAN STANLEY	106,607	89,222	-17,385 (-16.3%)
COMMONWEALTH EQUITY SERVICES, LLC	61,155	39,755	-21,400 (-35.0%)
BARCLAYS PLC	64,089	60,385	-3,704 (-5.8%)
BRIDGEWAY CAPITAL MANAGEMENT, LLC	76,700	72,700	-4,000 (-5.2%)
FMR LLC	15,455	12,858	-2,597 (-16.8%)
Tower Research Capital LLC (TRC)	12,982	10,810	-2,172 (-16.7%)
China Universal Asset Management Co., Ltd.	10,871	10,146	-725 (-6.7%)
Cetera Investment Advisers	27,760	27,260	-500 (-1.8%)
GF FUND MANAGEMENT CO. LTD.	1,334	1,277	-57 (-4.3%)
SBI Securities Co., Ltd.	2	1	-1 (-50.0%)
CWM, LLC	414	70	-344 (-83.1%)

Exited Positions (14)

STEMPOINT CAPITAL LP

Value ($000) $1,531 Shares 689,538

TANG CAPITAL MANAGEMENT LLC

Value ($000) $5,550 Shares 2,500,000

SCHULHOFF & CO INC

Value ($000) $611 Shares 275,000

PERCEPTIVE ADVISORS LLC

Value ($000) $2,616 Shares 1,178,307

DIADEMA PARTNERS LP

Value ($000) $333 Shares 150,000

PIER 88 INVESTMENT PARTNERS LLC

Value ($000) $337 Shares 151,730

Persistent Asset Partners Ltd

Value ($000) $77 Shares 34,632

DRIEHAUS CAPITAL MANAGEMENT LLC

Value ($000) $929 Shares 418,632

Walleye Capital LLC

Value ($000) $265 Shares 119,561

JACOBS LEVY EQUITY MANAGEMENT, INC

Value ($000) $134 Shares 60,333

PRUDENTIAL FINANCIAL INC

Value ($000) $36 Shares 16,300

AQR CAPITAL MANAGEMENT LLC

Value ($000) $31 Shares 13,832

EverSource Wealth Advisors, LLC

Value ($000) $1 Shares 434

ACADIAN ASSET MANAGEMENT LLC

Value ($000) $0 Shares 43,082

Institution	Prev Shares	Prev Value ($000)
STEMPOINT CAPITAL LP	689,538	$1,531
TANG CAPITAL MANAGEMENT LLC	2,500,000	$5,550
SCHULHOFF & CO INC	275,000	$611
PERCEPTIVE ADVISORS LLC	1,178,307	$2,616
DIADEMA PARTNERS LP	150,000	$333
PIER 88 INVESTMENT PARTNERS LLC	151,730	$337
Persistent Asset Partners Ltd	34,632	$77
DRIEHAUS CAPITAL MANAGEMENT LLC	418,632	$929
Walleye Capital LLC	119,561	$265
JACOBS LEVY EQUITY MANAGEMENT, INC	60,333	$134
PRUDENTIAL FINANCIAL INC	16,300	$36
AQR CAPITAL MANAGEMENT LLC	13,832	$31
EverSource Wealth Advisors, LLC	434	$1
ACADIAN ASSET MANAGEMENT LLC	43,082	$0