RAPPORT THERAPEUTICS INC

Ticker: RAPP CUSIP: 75383L102 Class: Common Stock

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 150,000 Value ($000) $4,551 Avg Close $27.68 Range $23.75 - $32.36

Q3 2025

Shares 450,000 Value ($000) $13,365 Avg Close $17.84 Range $11.05 - $42.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	150,000	$4,551	$27.68	$23.75 - $32.36
Q3 2025	450,000	$13,365	$17.84	$11.05 - $42.27