REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

STATE OF MICHIGAN RETIREMENT SYSTEM's Holding History (CIK: 0000762152)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 26,421 Value ($000) $20,394 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 27,521 Value ($000) $15,474 Avg Close $564.28 Range $519.56 - $609.69

Q2 2025

Shares 28,221 Value ($000) $14,816 Avg Close $556.12 Range $475.17 - $638.52

Q1 2025

Shares 28,521 Value ($000) $18,089 Avg Close $684.44 Range $615.89 - $745.12

Q4 2024

Shares 28,621 Value ($000) $20,388 Avg Close $834.60 Range $689.18 - $1055.74

Q3 2024

Shares 28,921 Value ($000) $30,403 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 29,021 Value ($000) $30,502 Avg Close $964.05 Range $870.40 - $1075.21

Q1 2024

Shares 28,921 Value ($000) $27,836 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 29,321 Value ($000) $25,752 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 29,997 Value ($000) $24,686 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 30,597 Value ($000) $21,985 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 30,897 Value ($000) $25,387 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 30,497 Value ($000) $22,003 Avg Close $733.79 Range $690.81 - $774.70

Q3 2022

Shares 31,497 Value ($000) $21,697 Avg Close $625.92 Range $560.71 - $750.51

Q2 2022

Shares 31,597 Value ($000) $18,678 Avg Close $646.43 Range $535.04 - $743.30

Q1 2022

Shares 30,297 Value ($000) $21,160 Avg Close $629.16 Range $589.59 - $706.29

Q4 2021

Shares 29,968 Value ($000) $18,925 Avg Close $611.44 Range $536.21 - $670.14

Q3 2021

Shares 27,292 Value ($000) $16,517 Avg Close $617.39 Range $551.89 - $682.83

Q2 2021

Shares 27,192 Value ($000) $15,188 Avg Close $503.83 Range $466.78 - $566.85

Q1 2021

Shares 27,192 Value ($000) $12,866 Avg Close $484.19 Range $438.57 - $555.83

Q4 2020

Shares 27,192 Value ($000) $13,137 Avg Close $536.82 Range $468.18 - $616.55

Q3 2020

Shares 27,392 Value ($000) $15,333 Avg Close $602.99 Range $537.02 - $660.97

Q2 2020

Shares 25,792 Value ($000) $16,085 Avg Close $564.49 Range $473.82 - $642.77

Q1 2020

Shares 18,344 Value ($000) $8,957 Avg Close $410.21 Range $326.32 - $515.14

Q4 2019

Shares 19,344 Value ($000) $7,263 Avg Close $334.59 Range $270.76 - $380.14

Q3 2019

Shares 19,244 Value ($000) $5,338 Avg Close $294.28 Range $269.87 - $318.99

Q2 2019

Shares 18,844 Value ($000) $5,898 Avg Close $331.08 Range $293.64 - $413.60

Q1 2019

Shares 22,544 Value ($000) $9,257 Avg Close $409.51 Range $363.99 - $439.56

Q4 2018

Shares 22,244 Value ($000) $8,308 Avg Close $364.00 Range $325.77 - $407.74

Q3 2018

Shares 23,044 Value ($000) $9,311 Avg Close $378.49 Range $340.69 - $414.19

Q2 2018

Shares 22,944 Value ($000) $7,915 Avg Close $311.03 Range $280.34 - $347.31

Q1 2018

Shares 22,744 Value ($000) $7,832 Avg Close $345.90 Range $311.80 - $394.59

Q4 2017

Shares 22,544 Value ($000) $8,476 Avg Close $402.77 Range $351.19 - $474.37

Q3 2017

Shares 23,344 Value ($000) $10,438 Avg Close $473.21 Range $424.12 - $523.22

Q2 2017

Shares 25,044 Value ($000) $12,300 Avg Close $435.19 Range $358.01 - $540.55

Q1 2017

Shares 24,944 Value ($000) $9,666 Avg Close $368.62 Range $338.21 - $399.00

Q4 2016

Shares 24,744 Value ($000) $9,083 Avg Close $378.17 Range $323.56 - $450.46

Q3 2016

Shares 109,200 Value ($000) $43,901 Avg Close $398.92 Range $346.51 - $441.54

Q2 2016

Shares 115,100 Value ($000) $40,196 Avg Close $383.00 Range $327.27 - $431.54

Q1 2016

Shares 101,900 Value ($000) $36,729 Avg Close $409.79 Range $347.04 - $529.97

Q4 2015

Shares 26,600 Value ($000) $14,440 Avg Close $538.82 Range $445.63 - $589.32

Q3 2015

Shares 27,900 Value ($000) $12,977 Avg Close $534.07 Range $433.12 - $602.59

Q2 2015

Shares 29,200 Value ($000) $14,896 Avg Close $485.93 Range $431.08 - $541.00

Q1 2015

Shares 28,500 Value ($000) $12,867 Avg Close $421.46 Range $390.83 - $492.77

Q4 2014

Shares 30,600 Value ($000) $12,554 Avg Close $391.09 Range $318.29 - $435.23

Q3 2014

Shares 30,200 Value ($000) $10,888 Avg Close $333.32 Range $283.49 - $367.27

Q2 2014

Shares 32,700 Value ($000) $9,237 Avg Close $294.74 Range $268.01 - $318.24

Q1 2014

Shares 32,100 Value ($000) $9,639 Avg Close $306.39 Range $261.52 - $350.55

Q4 2013

Shares 31,900 Value ($000) $8,780 Avg Close $286.03 Range $256.27 - $317.74

Q3 2013

Shares 31,700 Value ($000) $9,918 Avg Close $261.58 Range $224.53 - $318.07

Q2 2013

Shares 31,000 Value ($000) $6,971 Avg Close $231.58 Range $176.14 - $282.42

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	26,421	$20,394	$678.68	$540.32 - $792.77
Q3 2025	27,521	$15,474	$564.28	$519.56 - $609.69
Q2 2025	28,221	$14,816	$556.12	$475.17 - $638.52
Q1 2025	28,521	$18,089	$684.44	$615.89 - $745.12
Q4 2024	28,621	$20,388	$834.60	$689.18 - $1055.74
Q3 2024	28,921	$30,403	$1106.73	$1002.85 - $1204.52
Q2 2024	29,021	$30,502	$964.05	$870.40 - $1075.21
Q1 2024	28,921	$27,836	$945.64	$866.58 - $992.82
Q4 2023	29,321	$25,752	$818.96	$764.95 - $894.90
Q3 2023	29,997	$24,686	$781.58	$684.72 - $842.83
Q2 2023	30,597	$21,985	$766.75	$681.03 - $832.93
Q1 2023	30,897	$25,387	$750.05	$664.32 - $830.39
Q4 2022	30,497	$22,003	$733.79	$690.81 - $774.70
Q3 2022	31,497	$21,697	$625.92	$560.71 - $750.51
Q2 2022	31,597	$18,678	$646.43	$535.04 - $743.30
Q1 2022	30,297	$21,160	$629.16	$589.59 - $706.29
Q4 2021	29,968	$18,925	$611.44	$536.21 - $670.14
Q3 2021	27,292	$16,517	$617.39	$551.89 - $682.83
Q2 2021	27,192	$15,188	$503.83	$466.78 - $566.85
Q1 2021	27,192	$12,866	$484.19	$438.57 - $555.83
Q4 2020	27,192	$13,137	$536.82	$468.18 - $616.55
Q3 2020	27,392	$15,333	$602.99	$537.02 - $660.97
Q2 2020	25,792	$16,085	$564.49	$473.82 - $642.77
Q1 2020	18,344	$8,957	$410.21	$326.32 - $515.14
Q4 2019	19,344	$7,263	$334.59	$270.76 - $380.14
Q3 2019	19,244	$5,338	$294.28	$269.87 - $318.99
Q2 2019	18,844	$5,898	$331.08	$293.64 - $413.60
Q1 2019	22,544	$9,257	$409.51	$363.99 - $439.56
Q4 2018	22,244	$8,308	$364.00	$325.77 - $407.74
Q3 2018	23,044	$9,311	$378.49	$340.69 - $414.19
Q2 2018	22,944	$7,915	$311.03	$280.34 - $347.31
Q1 2018	22,744	$7,832	$345.90	$311.80 - $394.59
Q4 2017	22,544	$8,476	$402.77	$351.19 - $474.37
Q3 2017	23,344	$10,438	$473.21	$424.12 - $523.22
Q2 2017	25,044	$12,300	$435.19	$358.01 - $540.55
Q1 2017	24,944	$9,666	$368.62	$338.21 - $399.00
Q4 2016	24,744	$9,083	$378.17	$323.56 - $450.46
Q3 2016	109,200	$43,901	$398.92	$346.51 - $441.54
Q2 2016	115,100	$40,196	$383.00	$327.27 - $431.54
Q1 2016	101,900	$36,729	$409.79	$347.04 - $529.97
Q4 2015	26,600	$14,440	$538.82	$445.63 - $589.32
Q3 2015	27,900	$12,977	$534.07	$433.12 - $602.59
Q2 2015	29,200	$14,896	$485.93	$431.08 - $541.00
Q1 2015	28,500	$12,867	$421.46	$390.83 - $492.77
Q4 2014	30,600	$12,554	$391.09	$318.29 - $435.23
Q3 2014	30,200	$10,888	$333.32	$283.49 - $367.27
Q2 2014	32,700	$9,237	$294.74	$268.01 - $318.24
Q1 2014	32,100	$9,639	$306.39	$261.52 - $350.55
Q4 2013	31,900	$8,780	$286.03	$256.27 - $317.74
Q3 2013	31,700	$9,918	$261.58	$224.53 - $318.07
Q2 2013	31,000	$6,971	$231.58	$176.14 - $282.42