REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

GROUP ONE TRADING, L.P.'s Holding History (CIK: 0000932540)

Note: Option positions (PUT/CALL) are excluded.

Q2 2017
Shares 9,404 Value ($000) $9 Avg Close — Range —
Q1 2017
Shares 6,904 Value ($000) $11 Avg Close — Range —
Q4 2016
Shares 28,285 Value ($000) $64 Avg Close — Range —
Q3 2016
Shares 20,472 Value ($000) $68 Avg Close — Range —
Q2 2016
Shares 51,957 Value ($000) $150 Avg Close — Range —
Q1 2016
Shares 44,087 Value ($000) $306 Avg Close — Range —
Q4 2015
Shares 36,725 Value ($000) $320 Avg Close — Range —
Q3 2015
Shares 41,553 Value ($000) $272 Avg Close — Range —
Q2 2015
Shares 64,613 Value ($000) $708 Avg Close — Range —
Q1 2015
Shares 94,750 Value ($000) $1,605 Avg Close — Range —
Q4 2014
Shares 53,901 Value ($000) $865 Avg Close — Range —