REPARE THERAPEUTICS INC

Institution	Shares	Value ($000)
Yakira Capital Management, Inc.	266,601	$693
EQUITEC PROPRIETARY MARKETS, LLC	118,375	$308
MARSHALL WACE, LLP	1,115,744	$2,901
FNY Investment Advisers, LLC	35,000	$0
JANE STREET GROUP, LLC	278,304	$724
Walleye Capital LLC	106,683	$277
OCCUDO QUANTITATIVE STRATEGIES LP	13,548	$35
Covestor Ltd	13,627	$0
Point72 Asset Management, L.P.	51,252	$133
StoneX Group Inc.	10,603	$28
CURIO WEALTH, LLC	500	$1
Virtu Financial LLC	15,488	$0
HRT FINANCIAL LP	42,301	$0

Increased Positions (8)

Rangeley Capital, LLC

Value ($000) $3,348 (+194.6%) Shares 1,287,829 (+99.4%)

XTX Topco Ltd

Value ($000) $304 (+263.3%) Shares 116,933 (+145.9%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $868 (+4394.9%) Shares 333,694 (+2942.7%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $2,552 (+100.2%) Shares 981,360 (+35.5%)

TWO SIGMA ADVISERS, LP

Value ($000) $141 (+189.1%) Shares 54,200 (+95.7%)

Federation des caisses Desjardins du Quebec

Value ($000) $6 (+1187.9%) Shares 2,259 (+772.2%)

Engineers Gate Manager LP

Value ($000) $30 (+49.3%) Shares 11,627 (+1.1%)

ACADIAN ASSET MANAGEMENT LLC

Value ($000) $2 (+61.2%) Shares 618,672 (+8.9%)

Institution	Prev Shares	Curr Shares	Change
Rangeley Capital, LLC	645,876	1,287,829	+641,953 (+99.4%)
XTX Topco Ltd	47,547	116,933	+69,386 (+145.9%)
TWO SIGMA INVESTMENTS, LP	10,967	333,694	+322,727 (+2942.7%)
RENAISSANCE TECHNOLOGIES LLC	724,160	981,360	+257,200 (+35.5%)
TWO SIGMA ADVISERS, LP	27,700	54,200	+26,500 (+95.7%)
Federation des caisses Desjardins du Quebec	259	2,259	+2,000 (+772.2%)
Engineers Gate Manager LP	11,503	11,627	+124 (+1.1%)
ACADIAN ASSET MANAGEMENT LLC	568,301	618,672	+50,371 (+8.9%)

Decreased Positions (7)

CITADEL ADVISORS LLC

Value ($000) $621 (-49.5%) Shares 238,912 (-65.8%)

STIFEL FINANCIAL CORP

Value ($000) $26 (-81.0%) Shares 10,000 (-87.1%)

Squarepoint Ops LLC

Value ($000) $38 (-67.2%) Shares 14,485 (-77.8%)

BARCLAYS PLC

Value ($000) $1 (-95.2%) Shares 530 (-93.6%)

MORGAN STANLEY

Value ($000) $1 (-91.1%) Shares 404 (-94.0%)

BlackRock, Inc.

Value ($000) $375 (+45.4%) Shares 144,219 (-1.6%)

BANK OF AMERICA CORP /DE/

Value ($000) $28 (+23.4%) Shares 10,737 (-16.5%)

Institution	Prev Shares	Curr Shares	Change
CITADEL ADVISORS LLC	699,297	238,912	-460,385 (-65.8%)
STIFEL FINANCIAL CORP	77,600	10,000	-67,600 (-87.1%)
Squarepoint Ops LLC	65,243	14,485	-50,758 (-77.8%)
BARCLAYS PLC	8,330	530	-7,800 (-93.6%)
MORGAN STANLEY	6,738	404	-6,334 (-94.0%)
BlackRock, Inc.	146,550	144,219	-2,331 (-1.6%)
BANK OF AMERICA CORP /DE/	12,855	10,737	-2,118 (-16.5%)

Exited Positions (11)

Versant Venture Management, LLC

Value ($000) $4,658 Shares 2,646,657

MPM BioImpact LLC

Value ($000) $1,443 Shares 819,924

Affinity Asset Advisors, LLC

Value ($000) $352 Shares 200,000

Lantern Wealth Advisors, LLC

Value ($000) $35 Shares 20,000

Vontobel Holding Ltd.

Value ($000) $70 Shares 40,000

IEQ CAPITAL, LLC

Value ($000) $68 Shares 38,382

Blackstone Inc.

Value ($000) $46 Shares 25,957

SRS Capital Advisors, Inc.

Value ($000) $22 Shares 12,500

PRUDENTIAL FINANCIAL INC

Value ($000) $26 Shares 14,900

UBS Group AG

Value ($000) $6 Shares 3,553

GSA CAPITAL PARTNERS LLP

Value ($000) $0 Shares 13,862

Institution	Prev Shares	Prev Value ($000)
Versant Venture Management, LLC	2,646,657	$4,658
MPM BioImpact LLC	819,924	$1,443
Affinity Asset Advisors, LLC	200,000	$352
Lantern Wealth Advisors, LLC	20,000	$35
Vontobel Holding Ltd.	40,000	$70
IEQ CAPITAL, LLC	38,382	$68
Blackstone Inc.	25,957	$46
SRS Capital Advisors, Inc.	12,500	$22
PRUDENTIAL FINANCIAL INC	14,900	$26
UBS Group AG	3,553	$6
GSA CAPITAL PARTNERS LLP	13,862	$0