REPLIMUNE GROUP INC

Ticker: REPL CUSIP: 76029N106 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 11,045,336 Value ($000) $107,361 Avg Close $8.50 Range $4.14 - $11.26

Q3 2025

Shares 11,045,336 Value ($000) $46,280 Avg Close $6.39 Range $2.68 - $13.24

Q2 2025

Shares 11,045,336 Value ($000) $102,611 Avg Close $8.73 Range $6.44 - $10.75

Q1 2025

Shares 11,045,336 Value ($000) $107,692 Avg Close $12.38 Range $9.58 - $14.79

Q4 2024

Shares 11,045,336 Value ($000) $133,759 Avg Close $12.15 Range $9.94 - $17.00

Q3 2024

Shares 11,045,336 Value ($000) $121,057 Avg Close $10.16 Range $7.86 - $11.62

Q2 2024

Shares 10,045,336 Value ($000) $90,408 Avg Close $6.97 Range $4.92 - $9.76

Q1 2024

Shares 9,545,336 Value ($000) $77,985 Avg Close $8.20 Range $6.75 - $9.50

Q4 2023

Shares 9,545,336 Value ($000) $80,467 Avg Close $11.59 Range $5.89 - $17.01

Q3 2023

Shares 4,578,280 Value ($000) $78,334 Avg Close $19.64 Range $15.62 - $23.60

Q2 2023

Shares 4,578,280 Value ($000) $106,308 Avg Close $19.54 Range $15.51 - $24.81

Q1 2023

Shares 4,578,280 Value ($000) $80,852 Avg Close $23.78 Range $16.89 - $29.52

Q4 2022

Shares 4,578,280 Value ($000) $124,529 Avg Close $20.78 Range $16.68 - $28.17

Q3 2022

Shares 3,893,843 Value ($000) $67,247 Avg Close $19.07 Range $15.07 - $21.63

Q2 2022

Shares 3,591,081 Value ($000) $62,772 Avg Close $16.43 Range $13.05 - $20.54

Q1 2022

Shares 1,611,703 Value ($000) $27,367 Avg Close $18.87 Range $14.97 - $30.89

Q4 2021

Shares 593,395 Value ($000) $16,081 Avg Close $29.91 Range $24.85 - $35.93

Q3 2021

Shares 153,512 Value ($000) $4,550 Avg Close $32.48 Range $27.66 - $40.13

Q2 2021

Shares 153,512 Value ($000) $5,898 Avg Close $34.20 Range $28.18 - $40.22

Q1 2021

Shares 153,512 Value ($000) $4,684 Avg Close $37.45 Range $29.22 - $46.64

Q4 2020

Shares 153,512 Value ($000) $5,856 Avg Close $41.67 Range $22.01 - $54.85

Q3 2020

Shares 206,586 Value ($000) $4,756 Avg Close $22.79 Range $18.40 - $27.69

Q2 2020

Shares 5,141 Value ($000) $128 Avg Close $17.69 Range $9.28 - $26.22

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	11,045,336	$107,361	$8.50	$4.14 - $11.26
Q3 2025	11,045,336	$46,280	$6.39	$2.68 - $13.24
Q2 2025	11,045,336	$102,611	$8.73	$6.44 - $10.75
Q1 2025	11,045,336	$107,692	$12.38	$9.58 - $14.79
Q4 2024	11,045,336	$133,759	$12.15	$9.94 - $17.00
Q3 2024	11,045,336	$121,057	$10.16	$7.86 - $11.62
Q2 2024	10,045,336	$90,408	$6.97	$4.92 - $9.76
Q1 2024	9,545,336	$77,985	$8.20	$6.75 - $9.50
Q4 2023	9,545,336	$80,467	$11.59	$5.89 - $17.01
Q3 2023	4,578,280	$78,334	$19.64	$15.62 - $23.60
Q2 2023	4,578,280	$106,308	$19.54	$15.51 - $24.81
Q1 2023	4,578,280	$80,852	$23.78	$16.89 - $29.52
Q4 2022	4,578,280	$124,529	$20.78	$16.68 - $28.17
Q3 2022	3,893,843	$67,247	$19.07	$15.07 - $21.63
Q2 2022	3,591,081	$62,772	$16.43	$13.05 - $20.54
Q1 2022	1,611,703	$27,367	$18.87	$14.97 - $30.89
Q4 2021	593,395	$16,081	$29.91	$24.85 - $35.93
Q3 2021	153,512	$4,550	$32.48	$27.66 - $40.13
Q2 2021	153,512	$5,898	$34.20	$28.18 - $40.22
Q1 2021	153,512	$4,684	$37.45	$29.22 - $46.64
Q4 2020	153,512	$5,856	$41.67	$22.01 - $54.85
Q3 2020	206,586	$4,756	$22.79	$18.40 - $27.69
Q2 2020	5,141	$128	$17.69	$9.28 - $26.22