RETROPHIN INC

CUSIP: 761299106 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 205,000 Value ($000) $4,639 Avg Close — Range —
Q1 2016
Shares 150,000 Value ($000) $2,049 Avg Close — Range —
Q4 2015
Shares 345,000 Value ($000) $6,655 Avg Close — Range —
Q3 2015
Shares 370,000 Value ($000) $7,496 Avg Close — Range —
Q2 2015
Shares 460,000 Value ($000) $15,249 Avg Close — Range —
Q1 2015
Shares 500,000 Value ($000) $11,980 Avg Close — Range —
Q4 2014
Shares 920,000 Value ($000) $11,261 Avg Close — Range —
Q3 2014
Shares 1,000,000 Value ($000) $9,020,000 Avg Close — Range —
Q2 2014
Shares 1,216,400 Value ($000) $14,281 Avg Close — Range —
Q1 2014
Shares 1,153,230 Value ($000) $24,448 Avg Close — Range —