RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020

Shares 600 Value ($000) $17 Avg Close $25.42 Range $20.49 - $34.27

Q3 2020

Shares 600 Value ($000) $13 Avg Close $22.93 Range $18.00 - $32.24

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2020	600	$17	$25.42	$20.49 - $34.27
Q3 2020	600	$13	$22.93	$18.00 - $32.24