RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

VIRGINIA RETIREMENT SYSTEMS ET AL's Holding History (CIK: 0001005354)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 9,200 Value ($000) $985 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 6,700 Value ($000) $677 Avg Close $92.84 Range $62.84 - $106.52

Q4 2022

Shares 8,000 Value ($000) $233 Avg Close $25.70 Range $21.57 - $30.90

Q1 2022

Shares 11,800 Value ($000) $136 Avg Close $8.78 Range $6.01 - $12.61

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	9,200	$985	$106.08	$95.27 - $122.20
Q3 2025	6,700	$677	$92.84	$62.84 - $106.52
Q4 2022	8,000	$233	$25.70	$21.57 - $30.90
Q1 2022	11,800	$136	$8.78	$6.01 - $12.61