RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

ALLIANCEBERNSTEIN L.P.'s Holding History (CIK: 0001109448)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 930,233 Value ($000) $99,572 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 979,682 Value ($000) $98,938 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 61,470 Value ($000) $3,884 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 61,470 Value ($000) $3,256 Avg Close $55.48 Range $47.86 - $62.14

Q4 2024

Shares 61,470 Value ($000) $3,441 Avg Close $55.24 Range $46.80 - $68.58

Q3 2024

Shares 59,570 Value ($000) $3,121 Avg Close $47.92 Range $40.46 - $55.64

Q2 2024

Shares 61,070 Value ($000) $2,508 Avg Close $39.92 Range $35.17 - $45.92

Q1 2024

Shares 53,430 Value ($000) $2,315 Avg Close $43.76 Range $37.66 - $52.57

Q4 2023

Shares 54,390 Value ($000) $2,500 Avg Close $31.55 Range $20.97 - $50.27

Q3 2023

Shares 54,390 Value ($000) $1,247 Avg Close $22.39 Range $15.50 - $28.25

Q2 2023

Shares 54,390 Value ($000) $897 Avg Close $18.05 Range $15.52 - $21.67

Q1 2022

Shares 44,900 Value ($000) $517 Avg Close $8.78 Range $6.01 - $12.61

Q4 2021

Shares 44,800 Value ($000) $447 Avg Close $11.23 Range $8.44 - $14.21

Q3 2021

Shares 41,600 Value ($000) $543 Avg Close $15.27 Range $11.53 - $20.81

Q2 2021

Shares 41,600 Value ($000) $815 Avg Close $20.76 Range $18.19 - $23.35

Q1 2021

Shares 41,600 Value ($000) $885 Avg Close $29.00 Range $19.13 - $43.26

Q4 2020

Shares 40,100 Value ($000) $1,192 Avg Close $25.42 Range $20.49 - $34.27

Q3 2020

Shares 40,100 Value ($000) $869 Avg Close $22.93 Range $18.00 - $32.24

Q2 2020

Shares 41,300 Value ($000) $921 Avg Close $19.49 Range $14.12 - $25.86

Q1 2020

Shares 24,400 Value ($000) $371 Avg Close $17.90 Range $12.99 - $23.14

Q4 2019

Shares 24,400 Value ($000) $560 Avg Close $22.21 Range $19.06 - $25.84

Q3 2019

Shares 23,200 Value ($000) $501 Avg Close $21.45 Range $18.00 - $25.04

Q2 2019

Shares 18,700 Value ($000) $411 Avg Close $25.25 Range $20.64 - $29.13

Q1 2019

Shares 15,700 Value ($000) $430 Avg Close $28.74 Range $24.76 - $31.94

Q4 2018

Shares 16,600 Value ($000) $446 Avg Close $27.64 Range $23.44 - $32.00

Q3 2018

Shares 12,700 Value ($000) $370 Avg Close $31.60 Range $26.86 - $36.40

Q2 2018

Shares 7,300 Value ($000) $228 Avg Close $27.34 Range $16.80 - $37.23

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	930,233	$99,572	$106.08	$95.27 - $122.20
Q3 2025	979,682	$98,938	$92.84	$62.84 - $106.52
Q2 2025	61,470	$3,884	$61.23	$45.91 - $69.89
Q1 2025	61,470	$3,256	$55.48	$47.86 - $62.14
Q4 2024	61,470	$3,441	$55.24	$46.80 - $68.58
Q3 2024	59,570	$3,121	$47.92	$40.46 - $55.64
Q2 2024	61,070	$2,508	$39.92	$35.17 - $45.92
Q1 2024	53,430	$2,315	$43.76	$37.66 - $52.57
Q4 2023	54,390	$2,500	$31.55	$20.97 - $50.27
Q3 2023	54,390	$1,247	$22.39	$15.50 - $28.25
Q2 2023	54,390	$897	$18.05	$15.52 - $21.67
Q1 2022	44,900	$517	$8.78	$6.01 - $12.61
Q4 2021	44,800	$447	$11.23	$8.44 - $14.21
Q3 2021	41,600	$543	$15.27	$11.53 - $20.81
Q2 2021	41,600	$815	$20.76	$18.19 - $23.35
Q1 2021	41,600	$885	$29.00	$19.13 - $43.26
Q4 2020	40,100	$1,192	$25.42	$20.49 - $34.27
Q3 2020	40,100	$869	$22.93	$18.00 - $32.24
Q2 2020	41,300	$921	$19.49	$14.12 - $25.86
Q1 2020	24,400	$371	$17.90	$12.99 - $23.14
Q4 2019	24,400	$560	$22.21	$19.06 - $25.84
Q3 2019	23,200	$501	$21.45	$18.00 - $25.04
Q2 2019	18,700	$411	$25.25	$20.64 - $29.13
Q1 2019	15,700	$430	$28.74	$24.76 - $31.94
Q4 2018	16,600	$446	$27.64	$23.44 - $32.00
Q3 2018	12,700	$370	$31.60	$26.86 - $36.40
Q2 2018	7,300	$228	$27.34	$16.80 - $37.23