RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

SUSQUEHANNA INTERNATIONAL GROUP, LLP's Holding History (CIK: 0001446194)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,097 Value ($000) $439 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 3,104 Value ($000) $313 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 77,262 Value ($000) $4,882 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 82,980 Value ($000) $4,395 Avg Close $55.48 Range $47.86 - $62.14

Q4 2024

Shares 50,664 Value ($000) $2,836 Avg Close $55.24 Range $46.80 - $68.58

Q3 2024

Shares 21,481 Value ($000) $1,125 Avg Close $47.92 Range $40.46 - $55.64

Q2 2024

Shares 24,125 Value ($000) $991 Avg Close $39.92 Range $35.17 - $45.92

Q1 2024

Shares 103,253 Value ($000) $4,474 Avg Close $43.76 Range $37.66 - $52.57

Q4 2023

Shares 32,232 Value ($000) $1,482 Avg Close $31.55 Range $20.97 - $50.27

Q3 2023

Shares 30,456 Value ($000) $698 Avg Close $22.39 Range $15.50 - $28.25

Q2 2023

Shares 16,298 Value ($000) $269 Avg Close $18.05 Range $15.52 - $21.67

Q1 2023

Shares 784,555 Value ($000) $13,996 Avg Close $25.11 Range $15.95 - $34.99

Q4 2022

Shares 694,042 Value ($000) $20,211 Avg Close $25.70 Range $21.57 - $30.90

Q3 2022

Shares 214,522 Value ($000) $5,256 Avg Close $18.60 Range $4.08 - $30.98

Q2 2022

Shares 64,261 Value ($000) $267 Avg Close $5.47 Range $3.04 - $12.42

Q1 2022

Shares 17,671 Value ($000) $204 Avg Close $8.78 Range $6.01 - $12.61

Q4 2021

Shares 64,468 Value ($000) $643 Avg Close $11.23 Range $8.44 - $14.21

Q3 2021

Shares 53,203 Value ($000) $695 Avg Close $15.27 Range $11.53 - $20.81

Q2 2021

Shares 43,535 Value ($000) $852 Avg Close $20.76 Range $18.19 - $23.35

Q1 2021

Shares 123,737 Value ($000) $2,632 Avg Close $29.00 Range $19.13 - $43.26

Q4 2020

Shares 51,515 Value ($000) $1,532 Avg Close $25.42 Range $20.49 - $34.27

Q3 2020

Shares 69,266 Value ($000) $1,501 Avg Close $22.93 Range $18.00 - $32.24

Q2 2020

Shares 9,875 Value ($000) $220 Avg Close $19.49 Range $14.12 - $25.86

Q1 2020

Shares 15,705 Value ($000) $239 Avg Close $17.90 Range $12.99 - $23.14

Q3 2019

Shares 11,782 Value ($000) $254 Avg Close $21.45 Range $18.00 - $25.04

Q2 2019

Shares 14,930 Value ($000) $328 Avg Close $25.25 Range $20.64 - $29.13

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,097	$439	$106.08	$95.27 - $122.20
Q3 2025	3,104	$313	$92.84	$62.84 - $106.52
Q2 2025	77,262	$4,882	$61.23	$45.91 - $69.89
Q1 2025	82,980	$4,395	$55.48	$47.86 - $62.14
Q4 2024	50,664	$2,836	$55.24	$46.80 - $68.58
Q3 2024	21,481	$1,125	$47.92	$40.46 - $55.64
Q2 2024	24,125	$991	$39.92	$35.17 - $45.92
Q1 2024	103,253	$4,474	$43.76	$37.66 - $52.57
Q4 2023	32,232	$1,482	$31.55	$20.97 - $50.27
Q3 2023	30,456	$698	$22.39	$15.50 - $28.25
Q2 2023	16,298	$269	$18.05	$15.52 - $21.67
Q1 2023	784,555	$13,996	$25.11	$15.95 - $34.99
Q4 2022	694,042	$20,211	$25.70	$21.57 - $30.90
Q3 2022	214,522	$5,256	$18.60	$4.08 - $30.98
Q2 2022	64,261	$267	$5.47	$3.04 - $12.42
Q1 2022	17,671	$204	$8.78	$6.01 - $12.61
Q4 2021	64,468	$643	$11.23	$8.44 - $14.21
Q3 2021	53,203	$695	$15.27	$11.53 - $20.81
Q2 2021	43,535	$852	$20.76	$18.19 - $23.35
Q1 2021	123,737	$2,632	$29.00	$19.13 - $43.26
Q4 2020	51,515	$1,532	$25.42	$20.49 - $34.27
Q3 2020	69,266	$1,501	$22.93	$18.00 - $32.24
Q2 2020	9,875	$220	$19.49	$14.12 - $25.86
Q1 2020	15,705	$239	$17.90	$12.99 - $23.14
Q3 2019	11,782	$254	$21.45	$18.00 - $25.04
Q2 2019	14,930	$328	$25.25	$20.64 - $29.13