RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

Artisan Partners Limited Partnership's Holding History (CIK: 0001466153)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 263,591 Value ($000) $28,215 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 236,841 Value ($000) $23,919 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 174,479 Value ($000) $11,025 Avg Close $61.23 Range $45.91 - $69.89

Q2 2024

Shares 271,267 Value ($000) $11,138 Avg Close $39.92 Range $35.17 - $45.92

Q1 2024

Shares 271,421 Value ($000) $11,761 Avg Close $43.76 Range $37.66 - $52.57

Q4 2023

Shares 271,421 Value ($000) $12,477 Avg Close $31.55 Range $20.97 - $50.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	263,591	$28,215	$106.08	$95.27 - $122.20
Q3 2025	236,841	$23,919	$92.84	$62.84 - $106.52
Q2 2025	174,479	$11,025	$61.23	$45.91 - $69.89
Q2 2024	271,267	$11,138	$39.92	$35.17 - $45.92
Q1 2024	271,421	$11,761	$43.76	$37.66 - $52.57
Q4 2023	271,421	$12,477	$31.55	$20.97 - $50.27