RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

MetLife Investment Management, LLC's Holding History (CIK: 0001529735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 29,174 Value ($000) $3,123 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 30,362 Value ($000) $3,066 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 32,395 Value ($000) $2,047 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 32,414 Value ($000) $1,717 Avg Close $55.48 Range $47.86 - $62.14

Q4 2024

Shares 33,498 Value ($000) $1,875 Avg Close $55.24 Range $46.80 - $68.58

Q3 2024

Shares 31,652 Value ($000) $1,658 Avg Close $47.92 Range $40.46 - $55.64

Q2 2024

Shares 31,652 Value ($000) $1,300 Avg Close $39.92 Range $35.17 - $45.92

Q1 2024

Shares 27,123 Value ($000) $1,175 Avg Close $43.76 Range $37.66 - $52.57

Q4 2023

Shares 27,123 Value ($000) $1,247 Avg Close $31.55 Range $20.97 - $50.27

Q3 2023

Shares 27,123 Value ($000) $622 Avg Close $22.39 Range $15.50 - $28.25

Q2 2023

Shares 27,123 Value ($000) $447 Avg Close $18.05 Range $15.52 - $21.67

Q1 2022

Shares 24,442 Value ($000) $282 Avg Close $8.78 Range $6.01 - $12.61

Q4 2021

Shares 15,372 Value ($000) $153 Avg Close $11.23 Range $8.44 - $14.21

Q3 2021

Shares 15,372 Value ($000) $201 Avg Close $15.27 Range $11.53 - $20.81

Q2 2021

Shares 15,372 Value ($000) $301 Avg Close $20.76 Range $18.19 - $23.35

Q1 2021

Shares 15,372 Value ($000) $327 Avg Close $29.00 Range $19.13 - $43.26

Q4 2020

Shares 15,372 Value ($000) $457 Avg Close $25.42 Range $20.49 - $34.27

Q3 2020

Shares 15,372 Value ($000) $333 Avg Close $22.93 Range $18.00 - $32.24

Q2 2020

Shares 15,372 Value ($000) $343 Avg Close $19.49 Range $14.12 - $25.86

Q1 2020

Shares 13,465 Value ($000) $205 Avg Close $17.90 Range $12.99 - $23.14

Q4 2019

Shares 13,465 Value ($000) $309 Avg Close $22.21 Range $19.06 - $25.84

Q3 2019

Shares 11,256 Value ($000) $243 Avg Close $21.45 Range $18.00 - $25.04

Q2 2019

Shares 11,256 Value ($000) $248 Avg Close $25.25 Range $20.64 - $29.13

Q1 2019

Shares 6,192 Value ($000) $170 Avg Close $28.74 Range $24.76 - $31.94

Q4 2018

Shares 6,192 Value ($000) $166 Avg Close $27.64 Range $23.44 - $32.00

Q3 2018

Shares 6,192 Value ($000) $181 Avg Close $31.60 Range $26.86 - $36.40

Q4 2017

Shares 9,862 Value ($000) $287 Avg Close $26.40 Range $21.38 - $31.63

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	29,174	$3,123	$106.08	$95.27 - $122.20
Q3 2025	30,362	$3,066	$92.84	$62.84 - $106.52
Q2 2025	32,395	$2,047	$61.23	$45.91 - $69.89
Q1 2025	32,414	$1,717	$55.48	$47.86 - $62.14
Q4 2024	33,498	$1,875	$55.24	$46.80 - $68.58
Q3 2024	31,652	$1,658	$47.92	$40.46 - $55.64
Q2 2024	31,652	$1,300	$39.92	$35.17 - $45.92
Q1 2024	27,123	$1,175	$43.76	$37.66 - $52.57
Q4 2023	27,123	$1,247	$31.55	$20.97 - $50.27
Q3 2023	27,123	$622	$22.39	$15.50 - $28.25
Q2 2023	27,123	$447	$18.05	$15.52 - $21.67
Q1 2022	24,442	$282	$8.78	$6.01 - $12.61
Q4 2021	15,372	$153	$11.23	$8.44 - $14.21
Q3 2021	15,372	$201	$15.27	$11.53 - $20.81
Q2 2021	15,372	$301	$20.76	$18.19 - $23.35
Q1 2021	15,372	$327	$29.00	$19.13 - $43.26
Q4 2020	15,372	$457	$25.42	$20.49 - $34.27
Q3 2020	15,372	$333	$22.93	$18.00 - $32.24
Q2 2020	15,372	$343	$19.49	$14.12 - $25.86
Q1 2020	13,465	$205	$17.90	$12.99 - $23.14
Q4 2019	13,465	$309	$22.21	$19.06 - $25.84
Q3 2019	11,256	$243	$21.45	$18.00 - $25.04
Q2 2019	11,256	$248	$25.25	$20.64 - $29.13
Q1 2019	6,192	$170	$28.74	$24.76 - $31.94
Q4 2018	6,192	$166	$27.64	$23.44 - $32.00
Q3 2018	6,192	$181	$31.60	$26.86 - $36.40
Q4 2017	9,862	$287	$26.40	$21.38 - $31.63