RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 429,420 Value ($000) $45,965 Avg Close $106.08 Range $95.27 - $122.20

Q2 2025

Shares 170,832 Value ($000) $10,795 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 63,842 Value ($000) $3,382 Avg Close $55.48 Range $47.86 - $62.14

Q3 2023

Shares 4,146 Value ($000) $95 Avg Close $22.39 Range $15.50 - $28.25

Q1 2023

Shares 11,955 Value ($000) $213 Avg Close $25.11 Range $15.95 - $34.99

Q1 2018

Shares 180,000 Value ($000) $3,582 Avg Close $26.55 Range $19.25 - $32.35

Q4 2017

Shares 80,000 Value ($000) $2,325 Avg Close $26.40 Range $21.38 - $31.63

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	429,420	$45,965	$106.08	$95.27 - $122.20
Q2 2025	170,832	$10,795	$61.23	$45.91 - $69.89
Q1 2025	63,842	$3,382	$55.48	$47.86 - $62.14
Q3 2023	4,146	$95	$22.39	$15.50 - $28.25
Q1 2023	11,955	$213	$25.11	$15.95 - $34.99
Q1 2018	180,000	$3,582	$26.55	$19.25 - $32.35
Q4 2017	80,000	$2,325	$26.40	$21.38 - $31.63