RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

XPONANCE, INC.'s Holding History (CIK: 0001637541)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,269 Value ($000) $457 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 4,162 Value ($000) $420 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 4,272 Value ($000) $270 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 4,365 Value ($000) $231 Avg Close $55.48 Range $47.86 - $62.14

Q4 2024

Shares 4,168 Value ($000) $233 Avg Close $55.24 Range $46.80 - $68.58

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,269	$457	$106.08	$95.27 - $122.20
Q3 2025	4,162	$420	$92.84	$62.84 - $106.52
Q2 2025	4,272	$270	$61.23	$45.91 - $69.89
Q1 2025	4,365	$231	$55.48	$47.86 - $62.14
Q4 2024	4,168	$233	$55.24	$46.80 - $68.58