RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

Vanguard Personalized Indexing Management, LLC's Holding History (CIK: 0001767306)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,379 Value ($000) $255 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 2,068 Value ($000) $209 Avg Close $92.84 Range $62.84 - $106.52

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,379	$255	$106.08	$95.27 - $122.20
Q3 2025	2,068	$209	$92.84	$62.84 - $106.52