RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

Optiver Holding B.V.'s Holding History (CIK: 0001859606)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 92 Value ($000) $10 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 365 Value ($000) $37 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 221 Value ($000) $14 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 155 Value ($000) $8 Avg Close $55.48 Range $47.86 - $62.14

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	92	$10	$106.08	$95.27 - $122.20
Q3 2025	365	$37	$92.84	$62.84 - $106.52
Q2 2025	221	$14	$61.23	$45.91 - $69.89
Q1 2025	155	$8	$55.48	$47.86 - $62.14