RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

Nuveen, LLC's Holding History (CIK: 0001871926)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 115,934 Value ($000) $12,410 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 117,964 Value ($000) $11,913 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 121,855 Value ($000) $7,700 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 147,301 Value ($000) $7,803 Avg Close $55.48 Range $47.86 - $62.14

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	115,934	$12,410	$106.08	$95.27 - $122.20
Q3 2025	117,964	$11,913	$92.84	$62.84 - $106.52
Q2 2025	121,855	$7,700	$61.23	$45.91 - $69.89
Q1 2025	147,301	$7,803	$55.48	$47.86 - $62.14