SEPTERNA INC

Ticker: SEPN CUSIP: 81734D104 Class: Common Stock

BARCLAYS PLC's Holding History (CIK: 0000312069)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 38,147 Value ($000) $1,064 Avg Close $23.88 Range $17.55 - $30.50

Q2 2025

Shares 35,706 Value ($000) $377 Avg Close $8.24 Range $4.66 - $11.36

Q1 2025

Shares 22,733 Value ($000) $132 Avg Close $11.42 Range $4.17 - $23.85

Q4 2024

Shares 28,785 Value ($000) $659 Avg Close $23.65 Range $18.62 - $28.99

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	38,147	$1,064	$23.88	$17.55 - $30.50
Q2 2025	35,706	$377	$8.24	$4.66 - $11.36
Q1 2025	22,733	$132	$11.42	$4.17 - $23.85
Q4 2024	28,785	$659	$23.65	$18.62 - $28.99