SEPTERNA INC

Ticker: SEPN CUSIP: 81734D104 Class: Common Stock

NISA INVESTMENT ADVISORS, LLC's Holding History (CIK: 0000937615)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 341 Value ($000) $10 Avg Close $23.88 Range $17.55 - $30.50

Q3 2025

Shares 143 Value ($000) $3 Avg Close $13.12 Range $10.30 - $18.99

Q2 2025

Shares 143 Value ($000) $2 Avg Close $8.24 Range $4.66 - $11.36

Q1 2025

Shares 134 Value ($000) $1 Avg Close $11.42 Range $4.17 - $23.85

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	341	$10	$23.88	$17.55 - $30.50
Q3 2025	143	$3	$13.12	$10.30 - $18.99
Q2 2025	143	$2	$8.24	$4.66 - $11.36
Q1 2025	134	$1	$11.42	$4.17 - $23.85