SEPTERNA INC

Ticker: SEPN CUSIP: 81734D104 Class: Common Stock

DRIEHAUS CAPITAL MANAGEMENT LLC's Holding History (CIK: 0000938206)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,809,470 Value ($000) $134,088 Avg Close $23.88 Range $17.55 - $30.50

Q3 2025

Shares 4,919,896 Value ($000) $92,543 Avg Close $13.12 Range $10.30 - $18.99

Q2 2025

Shares 4,680,431 Value ($000) $49,472 Avg Close $8.24 Range $4.66 - $11.36

Q1 2025

Shares 3,122,608 Value ($000) $18,080 Avg Close $11.42 Range $4.17 - $23.85

Q4 2024

Shares 2,589,553 Value ($000) $59,301 Avg Close $23.65 Range $18.62 - $28.99

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,809,470	$134,088	$23.88	$17.55 - $30.50
Q3 2025	4,919,896	$92,543	$13.12	$10.30 - $18.99
Q2 2025	4,680,431	$49,472	$8.24	$4.66 - $11.36
Q1 2025	3,122,608	$18,080	$11.42	$4.17 - $23.85
Q4 2024	2,589,553	$59,301	$23.65	$18.62 - $28.99