SEPTERNA INC

Ticker: SEPN CUSIP: 81734D104 Class: Common Stock

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 44,070 Value ($000) $1,229 Avg Close $23.88 Range $17.55 - $30.50

Q4 2024

Shares 26,208 Value ($000) $600 Avg Close $23.65 Range $18.62 - $28.99

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	44,070	$1,229	$23.88	$17.55 - $30.50
Q4 2024	26,208	$600	$23.65	$18.62 - $28.99