SEPTERNA INC

Ticker: SEPN CUSIP: 81734D104 Class: Common Stock

VR Adviser, LLC's Holding History (CIK: 0001615982)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 610,808 Value ($000) $17,029 Avg Close $23.88 Range $17.55 - $30.50

Q3 2025

Shares 610,808 Value ($000) $11,489 Avg Close $13.12 Range $10.30 - $18.99

Q2 2025

Shares 540,453 Value ($000) $5,713 Avg Close $8.24 Range $4.66 - $11.36

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	610,808	$17,029	$23.88	$17.55 - $30.50
Q3 2025	610,808	$11,489	$13.12	$10.30 - $18.99
Q2 2025	540,453	$5,713	$8.24	$4.66 - $11.36