SEPTERNA INC

Ticker: SEPN CUSIP: 81734D104 Class: Common Stock

Nuveen, LLC's Holding History (CIK: 0001871926)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 25,798 Value ($000) $719 Avg Close $23.88 Range $17.55 - $30.50

Q3 2025

Shares 23,961 Value ($000) $451 Avg Close $13.12 Range $10.30 - $18.99

Q2 2025

Shares 57,971 Value ($000) $613 Avg Close $8.24 Range $4.66 - $11.36

Q1 2025

Shares 23,961 Value ($000) $139 Avg Close $11.42 Range $4.17 - $23.85

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	25,798	$719	$23.88	$17.55 - $30.50
Q3 2025	23,961	$451	$13.12	$10.30 - $18.99
Q2 2025	57,971	$613	$8.24	$4.66 - $11.36
Q1 2025	23,961	$139	$11.42	$4.17 - $23.85