SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 16,900 Value ($000) $2,941 Avg Close — Range —
Q1 2018
Shares 188,677 Value ($000) $28,186 Avg Close — Range —
Q2 2017
Shares 365,277 Value ($000) $60,369 Avg Close — Range —
Q1 2017
Shares 319,177 Value ($000) $55,610 Avg Close — Range —
Q1 2016
Shares 313,212 Value ($000) $53,841 Avg Close — Range —
Q4 2015
Shares 278,112 Value ($000) $57,013 Avg Close — Range —
Q3 2015
Shares 225,712 Value ($000) $46,323 Avg Close — Range —
Q2 2015
Shares 264,812 Value ($000) $63,949 Avg Close — Range —
Q1 2015
Shares 197,512 Value ($000) $47,263 Avg Close — Range —
Q3 2014
Shares 320,312 Value ($000) $82,977 Avg Close — Range —
Q2 2014
Shares 675,575 Value ($000) $159,091 Avg Close — Range —
Q1 2014
Shares 561,700 Value ($000) $83,429 Avg Close — Range —
Q4 2013
Shares 619,212 Value ($000) $87,488 Avg Close — Range —
Q3 2013
Shares 589,000 Value ($000) $70,615 Avg Close — Range —
Q2 2013
Shares 690,112 Value ($000) $65,637 Avg Close — Range —