SIENNA BIOPHARMACEUTICALS IN

Ticker: SNNAQ CUSIP: 82622H108 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019

Shares 586,294 Value ($000) $510 Avg Close $1.57 Range $0.83 - $2.47

Q1 2019

Shares 305,200 Value ($000) $708 Avg Close $2.71 Range $2.05 - $3.80

Q4 2018

Shares 118,600 Value ($000) $275 Avg Close $8.82 Range $2.23 - $15.18

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2019	586,294	$510	$1.57	$0.83 - $2.47
Q1 2019	305,200	$708	$2.71	$2.05 - $3.80
Q4 2018	118,600	$275	$8.82	$2.23 - $15.18