SILENCE THERAPEUTICS PLC

Ticker: SLN CUSIP: 82686Q101 Class: ADR

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 15,900 Value ($000) $97 Avg Close — Range —
Q3 2025
Shares 42,600 Value ($000) $221 Avg Close — Range —
Q2 2025
Shares 39,600 Value ($000) $230 Avg Close — Range —
Q1 2025
Shares 49,200 Value ($000) $139 Avg Close — Range —
Q4 2024
Shares 98,800 Value ($000) $680 Avg Close — Range —
Q3 2024
Shares 83,300 Value ($000) $1,514 Avg Close — Range —
Q2 2024
Shares 76,200 Value ($000) $1,448 Avg Close — Range —
Q1 2024
Shares 77,400 Value ($000) $1,672 Avg Close — Range —