SIONNA THERAPEUTICS INC

Ticker: SION CUSIP: 829401108 Class: Common Stock

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 69,424 Value ($000) $2,872 Avg Close $37.92 Range $24.65 - $45.00

Q3 2025

Shares 32,080 Value ($000) $943 Avg Close $21.76 Range $16.14 - $30.61

Q2 2025

Shares 38,038 Value ($000) $660 Avg Close $13.10 Range $7.25 - $18.85

Q1 2025

Shares 33,549 Value ($000) $351 Avg Close $16.34 Range $10.27 - $25.19

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	69,424	$2,872	$37.92	$24.65 - $45.00
Q3 2025	32,080	$943	$21.76	$16.14 - $30.61
Q2 2025	38,038	$660	$13.10	$7.25 - $18.85
Q1 2025	33,549	$351	$16.34	$10.27 - $25.19