SIONNA THERAPEUTICS INC

Ticker: SION CUSIP: 829401108 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,742 Value ($000) $236 Avg Close $37.92 Range $24.65 - $45.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,742	$236	$37.92	$24.65 - $45.00