SIONNA THERAPEUTICS INC

Ticker: SION CUSIP: 829401108 Class: Common Stock

DEERFIELD MANAGEMENT COMPANY, L.P.'s Holding History (CIK: 0001009258)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 970,590 Value ($000) $39,930 Avg Close $37.92 Range $24.65 - $45.00

Q3 2025

Shares 970,590 Value ($000) $28,545 Avg Close $21.76 Range $16.14 - $30.61

Q2 2025

Shares 970,590 Value ($000) $16,840 Avg Close $13.10 Range $7.25 - $18.85

Q1 2025

Shares 747,000 Value ($000) $7,814 Avg Close $16.34 Range $10.27 - $25.19

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	970,590	$39,930	$37.92	$24.65 - $45.00
Q3 2025	970,590	$28,545	$21.76	$16.14 - $30.61
Q2 2025	970,590	$16,840	$13.10	$7.25 - $18.85
Q1 2025	747,000	$7,814	$16.34	$10.27 - $25.19