SKYE BIOSCIENCE INC

Ticker: SKYE CUSIP: 83086J200 Class: Common Stock

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,331 Value ($000) $5 Avg Close $1.46 Range $0.68 - $4.99

Q2 2025

Shares 1,169 Value ($000) $0 Avg Close $2.07 Range $1.14 - $5.75

Q4 2024

Shares 17 Value ($000) $0 Avg Close $4.18 Range $2.31 - $5.96

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,331	$5	$1.46	$0.68 - $4.99
Q2 2025	1,169	$0	$2.07	$1.14 - $5.75
Q4 2024	17	$0	$4.18	$2.31 - $5.96