SOLENO THERAPEUTICS INC

Ticker: SLNO CUSIP: 834203309 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 5,278 Value ($000) $377 Avg Close $48.69 Range $41.50 - $73.97

Q4 2022

Shares 19,932 Value ($000) $39 Avg Close $1.24 Range $0.85 - $2.42

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	5,278	$377	$48.69	$41.50 - $73.97
Q4 2022	19,932	$39	$1.24	$0.85 - $2.42