SOPHIRIS BIO INC

CUSIP: 83578Q209 Class: FOREIGN CANADIAN

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 226,019 Value ($000) $84 Avg Close — Range —
Q2 2015
Shares 35,618 Value ($000) $28 Avg Close — Range —