SPERO THERAPEUTICS INC

Ticker: SPRO CUSIP: 84833T103 Class: COM

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP's Holding History (CIK: 0001164508)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 150,516 Value ($000) $283 Avg Close $2.20 Range $1.80 - $3.22

Q3 2020

Shares 34,225 Value ($000) $382 Avg Close $11.83 Range $8.50 - $14.37

Q2 2020

Shares 27,742 Value ($000) $375 Avg Close $11.23 Range $6.88 - $14.48

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	150,516	$283	$2.20	$1.80 - $3.22
Q3 2020	34,225	$382	$11.83	$8.50 - $14.37
Q2 2020	27,742	$375	$11.23	$6.88 - $14.48