SUMMIT THERAPEUTICS PLC

CUSIP: 86627R102 Class: Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 212,018 Value ($000) $2,349 Avg Close — Range —
Q3 2017
Shares 212,018 Value ($000) $2,654 Avg Close — Range —
Q2 2017
Shares 142,018 Value ($000) $1,561 Avg Close — Range —
Q1 2017
Shares 147,450 Value ($000) $1,967 Avg Close — Range —
Q4 2016
Shares 147,450 Value ($000) $1,262 Avg Close — Range —
Q3 2016
Shares 197,450 Value ($000) $1,813 Avg Close — Range —
Q2 2016
Shares 197,450 Value ($000) $1,562 Avg Close — Range —
Q1 2016
Shares 198,863 Value ($000) $1,392 Avg Close — Range —
Q4 2015
Shares 202,220 Value ($000) $2,321 Avg Close — Range —
Q3 2015
Shares 205,200 Value ($000) $2,136 Avg Close — Range —
Q2 2015
Shares 205,200 Value ($000) $2,280 Avg Close — Range —
Q1 2015
Shares 175,000 Value ($000) $2,168 Avg Close — Range —