SUMMIT THERAPEUTICS INC

Ticker: SMMT CUSIP: 86627T108 Class: Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025

Shares 13,149 Value ($000) $280 Avg Close $22.80 Range $15.55 - $36.91

Q3 2022

Shares 17,092 Value ($000) $20 Avg Close $1.13 Range $0.89 - $1.74

Q4 2021

Shares 19,474 Value ($000) $52 Avg Close $4.81 Range $2.23 - $5.79

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2025	13,149	$280	$22.80	$15.55 - $36.91
Q3 2022	17,092	$20	$1.13	$0.89 - $1.74
Q4 2021	19,474	$52	$4.81	$2.23 - $5.79