SYNDAX PHARMACEUTICALS INC

Ticker: SNDX CUSIP: 87164F105 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,219,609 Value ($000) $25,624 Avg Close $17.45 Range $12.99 - $22.73

Q3 2025

Shares 1,077,585 Value ($000) $16,579 Avg Close $13.09 Range $8.59 - $17.24

Q2 2025

Shares 644,542 Value ($000) $6,036 Avg Close $11.01 Range $8.58 - $14.24

Q1 2025

Shares 787,587 Value ($000) $9,676 Avg Close $14.10 Range $12.06 - $16.95

Q4 2024

Shares 184,117 Value ($000) $2,434 Avg Close $17.11 Range $12.40 - $22.50

Q3 2024

Shares 352,358 Value ($000) $6,783 Avg Close $20.66 Range $17.34 - $25.07

Q2 2024

Shares 146,643 Value ($000) $3,011 Avg Close $20.93 Range $18.65 - $24.38

Q1 2024

Shares 8,524 Value ($000) $203 Avg Close $22.30 Range $19.58 - $25.34

Q4 2023

Shares 41,965 Value ($000) $907 Avg Close $15.37 Range $11.21 - $21.84

Q3 2023

Shares 148,572 Value ($000) $2,157 Avg Close $18.92 Range $12.85 - $23.55

Q2 2023

Shares 173,019 Value ($000) $3,621 Avg Close $20.82 Range $19.27 - $23.14

Q1 2023

Shares 139,067 Value ($000) $2,937 Avg Close $24.88 Range $20.01 - $29.86

Q4 2022

Shares 160,435 Value ($000) $4,083 Avg Close $23.32 Range $20.25 - $26.51

Q3 2022

Shares 128,028 Value ($000) $3,077 Avg Close $22.44 Range $18.05 - $25.71

Q4 2021

Shares 123,303 Value ($000) $2,699 Avg Close $18.48 Range $14.76 - $22.71

Q3 2021

Shares 337,146 Value ($000) $6,443 Avg Close $16.66 Range $13.58 - $20.32

Q2 2021

Shares 410,467 Value ($000) $7,048 Avg Close $18.32 Range $13.02 - $25.46

Q1 2021

Shares 573,938 Value ($000) $12,833 Avg Close $22.59 Range $19.05 - $25.68

Q4 2020

Shares 655,007 Value ($000) $14,568 Avg Close $20.74 Range $13.92 - $27.85

Q3 2020

Shares 249,427 Value ($000) $3,682 Avg Close $15.24 Range $13.04 - $17.99

Q2 2020

Shares 100,591 Value ($000) $1,491 Avg Close $15.23 Range $8.72 - $21.97

Q1 2020

Shares 77,573 Value ($000) $851 Avg Close $9.38 Range $6.32 - $12.27

Q4 2019

Shares 63,733 Value ($000) $559 Avg Close $7.34 Range $5.35 - $9.47

Q4 2017

Shares 23,063 Value ($000) $202 Avg Close $9.90 Range $7.70 - $13.48

Q3 2017

Shares 15,630 Value ($000) $183 Avg Close $12.26 Range $10.56 - $14.17

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,219,609	$25,624	$17.45	$12.99 - $22.73
Q3 2025	1,077,585	$16,579	$13.09	$8.59 - $17.24
Q2 2025	644,542	$6,036	$11.01	$8.58 - $14.24
Q1 2025	787,587	$9,676	$14.10	$12.06 - $16.95
Q4 2024	184,117	$2,434	$17.11	$12.40 - $22.50
Q3 2024	352,358	$6,783	$20.66	$17.34 - $25.07
Q2 2024	146,643	$3,011	$20.93	$18.65 - $24.38
Q1 2024	8,524	$203	$22.30	$19.58 - $25.34
Q4 2023	41,965	$907	$15.37	$11.21 - $21.84
Q3 2023	148,572	$2,157	$18.92	$12.85 - $23.55
Q2 2023	173,019	$3,621	$20.82	$19.27 - $23.14
Q1 2023	139,067	$2,937	$24.88	$20.01 - $29.86
Q4 2022	160,435	$4,083	$23.32	$20.25 - $26.51
Q3 2022	128,028	$3,077	$22.44	$18.05 - $25.71
Q4 2021	123,303	$2,699	$18.48	$14.76 - $22.71
Q3 2021	337,146	$6,443	$16.66	$13.58 - $20.32
Q2 2021	410,467	$7,048	$18.32	$13.02 - $25.46
Q1 2021	573,938	$12,833	$22.59	$19.05 - $25.68
Q4 2020	655,007	$14,568	$20.74	$13.92 - $27.85
Q3 2020	249,427	$3,682	$15.24	$13.04 - $17.99
Q2 2020	100,591	$1,491	$15.23	$8.72 - $21.97
Q1 2020	77,573	$851	$9.38	$6.32 - $12.27
Q4 2019	63,733	$559	$7.34	$5.35 - $9.47
Q4 2017	23,063	$202	$9.90	$7.70 - $13.48
Q3 2017	15,630	$183	$12.26	$10.56 - $14.17