SYNDAX PHARMACEUTICALS INC

Ticker: SNDX CUSIP: 87164F105 Class: Common Stock

Palo Alto Investors LP's Holding History (CIK: 0001306923)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 794,507 Value ($000) $16,693 Avg Close $17.45 Range $12.99 - $22.73

Q3 2025

Shares 654,930 Value ($000) $10,076 Avg Close $13.09 Range $8.59 - $17.24

Q2 2025

Shares 444,367 Value ($000) $4,161 Avg Close $11.01 Range $8.58 - $14.24

Q1 2025

Shares 444,367 Value ($000) $5,459 Avg Close $14.10 Range $12.06 - $16.95

Q4 2024

Shares 405,193 Value ($000) $5,357 Avg Close $17.11 Range $12.40 - $22.50

Q3 2024

Shares 405,193 Value ($000) $7,800 Avg Close $20.66 Range $17.34 - $25.07

Q2 2024

Shares 405,193 Value ($000) $8,319 Avg Close $20.93 Range $18.65 - $24.38

Q1 2024

Shares 405,193 Value ($000) $9,644 Avg Close $22.30 Range $19.58 - $25.34

Q4 2023

Shares 472,600 Value ($000) $10,213 Avg Close $15.37 Range $11.21 - $21.84

Q3 2023

Shares 472,600 Value ($000) $6,862 Avg Close $18.92 Range $12.85 - $23.55

Q2 2023

Shares 612,600 Value ($000) $12,822 Avg Close $20.82 Range $19.27 - $23.14

Q1 2023

Shares 612,600 Value ($000) $12,938 Avg Close $24.88 Range $20.01 - $29.86

Q4 2022

Shares 612,600 Value ($000) $15,591 Avg Close $23.32 Range $20.25 - $26.51

Q3 2022

Shares 612,600 Value ($000) $14,721 Avg Close $22.44 Range $18.05 - $25.71

Q2 2022

Shares 612,600 Value ($000) $11,786 Avg Close $16.66 Range $13.27 - $19.91

Q1 2022

Shares 612,600 Value ($000) $10,647 Avg Close $16.84 Range $14.56 - $22.27

Q4 2021

Shares 598,900 Value ($000) $13,110 Avg Close $18.48 Range $14.76 - $22.71

Q3 2021

Shares 444,900 Value ($000) $8,502 Avg Close $16.66 Range $13.58 - $20.32

Q2 2021

Shares 401,100 Value ($000) $6,887 Avg Close $18.32 Range $13.02 - $25.46

Q1 2021

Shares 264,200 Value ($000) $5,908 Avg Close $22.59 Range $19.05 - $25.68

Q4 2020

Shares 264,200 Value ($000) $5,876 Avg Close $20.74 Range $13.92 - $27.85

Q3 2020

Shares 198,400 Value ($000) $2,928 Avg Close $15.24 Range $13.04 - $17.99

Q2 2020

Shares 127,700 Value ($000) $1,893 Avg Close $15.23 Range $8.72 - $21.97

Q1 2020

Shares 66,100 Value ($000) $725 Avg Close $9.38 Range $6.32 - $12.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	794,507	$16,693	$17.45	$12.99 - $22.73
Q3 2025	654,930	$10,076	$13.09	$8.59 - $17.24
Q2 2025	444,367	$4,161	$11.01	$8.58 - $14.24
Q1 2025	444,367	$5,459	$14.10	$12.06 - $16.95
Q4 2024	405,193	$5,357	$17.11	$12.40 - $22.50
Q3 2024	405,193	$7,800	$20.66	$17.34 - $25.07
Q2 2024	405,193	$8,319	$20.93	$18.65 - $24.38
Q1 2024	405,193	$9,644	$22.30	$19.58 - $25.34
Q4 2023	472,600	$10,213	$15.37	$11.21 - $21.84
Q3 2023	472,600	$6,862	$18.92	$12.85 - $23.55
Q2 2023	612,600	$12,822	$20.82	$19.27 - $23.14
Q1 2023	612,600	$12,938	$24.88	$20.01 - $29.86
Q4 2022	612,600	$15,591	$23.32	$20.25 - $26.51
Q3 2022	612,600	$14,721	$22.44	$18.05 - $25.71
Q2 2022	612,600	$11,786	$16.66	$13.27 - $19.91
Q1 2022	612,600	$10,647	$16.84	$14.56 - $22.27
Q4 2021	598,900	$13,110	$18.48	$14.76 - $22.71
Q3 2021	444,900	$8,502	$16.66	$13.58 - $20.32
Q2 2021	401,100	$6,887	$18.32	$13.02 - $25.46
Q1 2021	264,200	$5,908	$22.59	$19.05 - $25.68
Q4 2020	264,200	$5,876	$20.74	$13.92 - $27.85
Q3 2020	198,400	$2,928	$15.24	$13.04 - $17.99
Q2 2020	127,700	$1,893	$15.23	$8.72 - $21.97
Q1 2020	66,100	$725	$9.38	$6.32 - $12.27